Nifedipine (API)
21829-25-4
C17H18N2O6
Yellow crystalline powder
Nifedipine is a widely used calcium channel blocker that belongs to the class of dihydropyridine derivatives. It is primarily used in the treatment of cardiovascular conditions, particularly hypertension (high blood pressure) and angina pectoris (chest pain). Nifedipine works by inhibiting the influx of calcium ions into smooth muscle cells in the blood vessels and heart. This action causes blood vessels to dilate (relax), which lowers the resistance the heart has to work against, ultimately reducing the heart's workload and improving blood flow. The result is a reduction in blood pressure and relief from angina symptoms.
Treatment of hypertension (high blood pressure)
Nifedipine effectively lowers blood pressure by relaxing the blood vessels, preventing the risks associated with elevated blood pressure such as stroke, heart failure, and kidney damage.
Management of angina pectoris
It is used to treat both stable angina and variant angina (Prinzmetal's angina) by improving oxygen supply to the heart muscle and reducing pain.
Prevention of chronic stable angina
Regular use of Nifedipine helps prevent the recurrence of angina attacks, improving quality of life in patients with coronary artery disease.
Off-label uses
Nifedipine is also explored in the treatment of certain types of Raynaud's phenomenon and preterm labor.
Manufactured in GMP-certified facilities
Nifedipine API is produced in facilities that comply withGMP standards, ensuring consistent and high-quality production processes.
01
Complies with international pharmacopoeial standards
The product adheres to recognized pharmacopeial standards such as the USP and EP, ensuring its safety and efficacy.
02
Purity ≥99%
Nifedipine API meets stringent purity requirements, ensuring that the active ingredient is of high quality for pharmaceutical use.
03
Rigorous testing
The product undergoes comprehensive testing to determine potency, impurities, and stability, ensuring it meets all quality specifications before distribution.
04
Store in a cool, dry place
Nifedipine should be stored in an environment where the temperature does not exceed room temperature, with humidity kept to a minimum to preserve its quality.
Keep away from direct sunlight and moisture
Exposure to light and moisture can degrade the product and reduce its efficacy.
Ensure airtight packaging
To maintain the product's stability and prevent contamination, Nifedipine should be stored in airtight packaging. Proper packaging ensures long-term storage without compromising its therapeutic properties.
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